Archive for the ‘Flouridation and osteosarcoma’ Category

No to fluoride

Comments Off
Posted 26 Oct 2010 — by James Street
Category Etiology and cause of osteosarcoma, Flouridation and osteosarcoma
© newsminer.com 2010

Fluoride Linked to Bone Cancer, Yet Again

Comments Off
Posted 14 Aug 2010 — by James Street
Category Etiology and cause of osteosarcoma, Flouridation and osteosarcoma

Another Study Links Fluoride to Osteosarcoma

05.29.2009 – Blood fluoride levels were significantly higher in patients with osteosarcoma than in control groups, according to research published in Biological Trace Element Research (April 2009). Osteosarcoma, a rare bone cancer, occurs mostly in children and young adults.

Sandhu and colleagues measured serum fluoride levels in three equal groups of age-matched and sex-matched patients. Group one had osteosarcoma; group two had non-osteosarcoma bone tumors; and group three had musculo-skeletal pain. (1)

“Mean serum fluoride concentration was found to be significantly higher in patients with osteosarcoma as compared to the other two groups,” write Sandhu’s team. “(T)his report proves a link between raised fluoride levels in serum and osteosarcoma,” they write.

This reinforces a 2006 published Harvard study by Bassin showing a link between water fluoridation and osteosarcoma in young boys. (2)

A 1992 New Jersey Department of Health study shows osteosarcoma rates higher among young males in fluoridated vs. unfluoridated regions of New Jersey. (3)

More studies link fluoride to bone and other cancers but are downplayed or ignored by government officials. (4)(5)

Bone defects similar to bone cancer were detected in fluoridated Newburgh NY children as early as 1955. Newburgh is home of the first human health fluoridation experiment begun in 1945.

According to Christopher Bryson in The Fluoride Deception. “A radiologist, Dr. John Caffey of Columbia University, called the defects ‘striking’ in their ‘similarity’ to bone cancer… and seen more than twice as frequently among boys in Newburgh as among boys in nonfluoridated Kingston [the control city].” (6)

In 2006, the prestigious National Research Council review of fluoride/fluoridation toxicology found a fluoride/bone cancer link plausible.

“If governments truly want to save money, stopping fluoridation is a no-brainer. It would save money, preserve health and teeth,” says attorney Paul Beeber, President, New York State Coalition Opposed to Fluoridation.

In 2005, 11 Environmental Protection Agency (EPA) employee unions, representing over 7000 environmental and public health professionals called for a moratorium on fluoridation programs across the country and asked EPA management to recognize fluoride as posing a serious risk of causing cancer in people. (7)

In addition, 2,470 professionals urge the US Congress to stop fluoridation until Congressional hearings are conducted, citing scientific evidence that fluoridation, long promoted to fight tooth decay, is ineffective and has serious health risks. See statement:

http://www.fluoridealert.org/statement.august.2007.html

Join them at http://congress.FluorideAction.Net

References:

1) Biological Trace Element Research, “Serum Fluoride and Sialic Acid Levels in Osteosarcoma,” by Sandhu R, Lal H, Kundu ZS, Kharb S, Apr 24, 2009 [Epub ahead of print]

2) Cancer Causes Control “Age-specific fluoride exposure in drinking water and
osteosarcoma (United States), by Bassin et al., May 2006

3) New Jersey Department of Health, “A Brief Report On The Association Of Drinking Water Fluoridation And The Incidence of Osteosarcoma Among Young Males,” Cohn PD. (1992).

4) Fluoride and Osteosarcoma

http://www.fluoridealert.org/health/cancer/osteosarcoma-timeline.html

5) Fluoride and Cancer

http://www.fluoridealert.org/health/cancer/

6) The Fluoride Deception, by Christopher Bryson
with a foreword by Dr. Theo Colborn, Seven Stories Press,
May 2004

http://www.fluoridealert.org/fluoride-deception.htm

7) Press Release August 19, 2005, “EPA Unions Call for Nationwide Moratorium on Fluoridation, Congressional Hearing on Adverse Effects, Youth Cancer Cover Up,” Contact: Dr. William Hirzy, Vice-President NTEU Chapter 280

http://www.nteu280.org/Issues/Fluoride/Press%20Release.%20Fluoride.htm

Contact: Paul Beeber, JD nyscof@aol.com

President,

New York State Coalition Opposed to Fluoridation, Inc

PO Box 263

Old Bethpage, NY 11804

http://www.orgsites.com/ny/nyscof

http://www.FluorideAction.Net

Fluoride/Osteosarcoma Link is Plausible

Comments Off
Posted 14 Aug 2010 — by James Street
Category Etiology and cause of osteosarcoma, Flouridation and osteosarcoma

By nyscof

“Fluoride appears to have the potential to initiate or promote cancers, particularly of the bone…,” according to the most recent and extensive review of fluoride toxicology by the prestigious National Research Council (NRC). (1)

Fluoride chemicals are added to about 70% of public water supplies ostensibly to reduce tooth decay, not to purify the water.

In 2006, the NRC found the.The Environmental Protection Agency’s Maximum Contaminant Level Goal (MCLG) for fluoride is too high to be protective of health (4 mg/L) and must be lowered. EPA scientists have been saying this since 1986; but EPA management caved to political pressure and over-ruled its scientists. EPA is long overdue in revising fluoride’s MCLG based on the 2006 NRC Fluoride Report, which was done at EPA’s request.

According to Bill Hirzy, PhD, retired EPA scientist, “Since 1986 the [EPA HQ professionals] union has taken exception to EPA’s unscientific approach to dealing with the toxicity of fluoride in order to protect the USPHS [Public Health Service] program of national water fluoridation.” (2)

Hirzy writes, “When I last spoke with the Division Director responsible for that risk assessment he told me EPA was waiting for a paper, promised three years ago by its principal first author, that would counter an epidemiology study done under that very author’s direction at Harvard.”

Hirzy is talking about a published peer-reviewed study by Bassin (2a) which links fluoridation to osteosarcoma (bone cancer). Chester Douglass, Bassin’s Harvard University advisor and, at that time, employee of Colgate (sellers of fluoridated dental products) signed off on Bassin’s work. But, Douglass told the NRC panel that no such study existed, according to the Environmental Working Group.(3)

The whole fluoridation program appears to rest upon the shoulders of Chester Douglass whose much anticipated osteosarcoma/fluoridation research has yet to be published even though it was promised years ago, costing tax payers millions of dollars.

But, there’s more evidence linking fluoride to osteosarcoma (See: http://www.fluoridealert.org/health/cancer/osteosarcoma.html ) and loads of evidence linking fluoride to adverse health effects – even at low doses added to public (and some bottled) water supplies (See: http://www.fluoridealert.org/health/ )

At least three members of the NRC fluoride panel believe the MCLG for fluoride should be zero.

In a different study, Ramesh and colleagues propose that high fluoride bone content might have been one of the major factors causing osteosarcoma in people living in India where water supplies are often high in natural fluoride (Journal of Environmental Pathology, Toxicology and Oncology, 2001) (5)

The high levels of bone fluoride levels and the similarity of the mechanisms of action between fluoride-induced DNA damage and chemically-induced p53 mutations lead us to propose that high fluoride bone content might have been one of the major factors causing osteosarcoma, they write.

Mutations in the p53 genes are the most commonly observed genetic alterations in human cancer. Ramesh concludes that fluoride probably causes mutations in p53.

In another study published in the July 2001 “Journal of Epidemiology,” Takahashi and colleagues write, “The likelihood of fluoride acting as a genetic cause of cancer requires consideration.” (4)

Takahashi’s team report that the National Cancer Institute provided epidemiological evidence of a relation between cancer incidence and water fluoridation in 1987. These findings provoked a 1990 National Toxicology Program (NTP) study that determined fluoride could be a cancer-causing agent.

The NTP study “supplied a detailed description of the toxicology of fluoride, not only in terms of osteosarcoma, but also lesions in the oral mucosa, thyroid gland, skin and uterus…(which) prompted us to re-test the hypothesis of an epidemiological association between water fluoridation and cancer incidences…”, wrote Takahashi who found fluoridation status positively correlates to cancers of the oral cavity, pharynx, colon, rectum, hepato-bilary & urinary organs and bone cancer in males.

Such a broad spectrum association has never been observed for any particular known carcinogen, but it may be reasonable for fluoride, because of its strong electronegative nature, the authors explain.

Some studies, e.g., Hoover (1976) and Knox (1985) claim no credible fluoridation/cancer association exists. However, Takahashi and co-authors found the Hoover/Knox assessments flawed, and explain why in their paper.

After ten years of water fluoridation, children aged 7-18 in Newburg, N.Y., had more cortical bone defects than the non-fluoridated control city, Kingston. And more osteosarcoma occurred in young males in

fluoridated portions of New Jersey. … these two facts may be connected pathophysiologically, Takahashi reports.

An April 2009 research paper (Biological Trace Element Research) reports blood fluoride levels were significantly higher in patients with osteosarcoma than in control groups. Sandhu and colleagues measured serum fluoride levels in three equal groups of age-matched and sex-matched patients. Group one had osteosarcoma; group two had non-osteosarcoma bone tumors; and group three had musculo-skeletal pain. (6)

“Mean serum fluoride concentration was found to be significantly higher in patients with osteosarcoma as compared to the other two groups,” write Sandhu’s team. “(T)his report proves a link between raised fluoride levels in serum and osteosarcoma,” they write.

Take action to end fluoridation here: http://congress.FluorideAction.Net

More information about fluoride and cancer:

http://www.fluoridealert.org/health/cancer/

References:

1) Fluoride in Drinking Water:A Scientific Review of EPA’s Standards

http://www.nap.edu/catalog.php?record_id=11571

2) Science Progress “Dude, Where’s My War on Science? An Attack on EPA’s Policy Process Fails Peer Review.”

Comment #7 by Bill Hirzy

http://www.scienceprogress.org/2009/07/dude-wheres-my-war-on-science/

2a) Bassin EB, Wypij D, Davis RB, Mittleman MA. (2006). Age-specific Fluoride Exposure in Drinking Water and Osteosarcoma (United States). Cancer Causes and Control 17: 421-8.

3) Environmental Working Group “Harvard Fluoride Findings Misrepresented?”

http://www.ewg.org/node/8761

(4) J Epidemiol. 2001 Jul;11(4):170-9.Regression analysis of cancer incidence rates and water fluoride in the U.S.A. based on IACR/IARC (WHO) data (1978-1992). International Agency for Research on Cancer, by Takahashi K, Akiniwa K, Narita K.

(5) J Environ Pathol Toxicol Oncol. 2001;20(3):237-43.

Low levels of p53 mutations in Indian patients with osteosarcoma and the correlation with fluoride levels in bone, by

Ramesh N, Vuayaraghavan AS, Desai BS, Natarajan M, Murthy PB, Pillai KS.

6) Biological Trace Element Research, “Serum Fluoride and Sialic Acid Levels in Osteosarcoma,” by Sandhu R, Lal H, Kundu ZS, Kharb S, Apr 24, 2009 [published online]

http://www.ncbi.nlm.nih.gov/pubmed/19390788

The Absurdities of Water Fluoridation

Posted 15 Mar 2010 — by James Street
Category Flouridation and osteosarcoma, Molecular Osteosarcoma Studies
ater fluoridation is a peculiarly American phenomenon. It started at a time when Asbestos lined our pipes, lead was added to gasoline, PCBs filled our transformers and DDT was deemed so “safe and effective” that officials felt no qualms spraying kids in school classrooms and seated at picnic tables. One by one all these chemicals have been banned, but fluoridation remains untouched.
By Paul Connett, PhD

Toronto adds poisonous fluoride to your drinking water. It’s a toxic waste product and many health officials decry its use as causing bone cancer, mottled teeth and for being ineffective at reducing cavities when drunk.

Water fluoridation is a peculiarly American phenomenon. It started at a time when Asbestos lined our pipes, lead was added to gasoline, PCBs filled our transformers and DDT was deemed so “safe and effective” that officials felt no qualms spraying kids in school classrooms and seated at picnic tables. One by one all these chemicals have been banned, but fluoridation remains untouched.

For over 50 years US government officials have confidently and enthusiastically claimed that fluoridation is “safe and effective”. However, they are seldom prepared to defend the practice in open public debate. Actually, there are so many arguments against fluoridation that it can get overwhelming.

To simplify things it helps to separate the ethical from the scientific arguments.

For those for whom ethical concerns are paramount, the issue of fluoridation is very simple to resolve. It is simply not ethical; we simply shouldn’t be forcing medication on people without their “informed consent”. The bad news is that ethical arguments are not very influential in Washington, DC unless politicians are very conscious of millions of people watching them. The good news is that the ethical arguments are buttressed by solid common sense arguments and scientific studies which convincingly show that fluoridation is neither “safe and effective” nor necessary. I have summarized the arguments in several categories:

Fluoridation is UNETHICAL because:

1) It violates the individual’s right to informed consent to medication.
2) The municipality cannot control the dose of the patient.
3) The municipality cannot track each individual’s response.
4) It ignores the fact that some people are more vulnerable to fluoride’s toxic effects than others. Some people will suffer while others may benefit.
5) It violates the Nuremberg code for human experimentation.

As stated by the recent recipient of the Nobel Prize for Medicine (2000), Dr. Arvid Carlsson:

“I am quite convinced that water fluoridation, in a not-too-distant future, will be consigned to medical history…Water fluoridation goes against leading principles of pharmacotherapy, which is progressing from a stereotyped medication – of the type 1 tablet 3 times a day – to a much more individualized therapy as regards both dosage and selection of drugs. The addition of drugs to the drinking water means exactly the opposite of an individualized therapy.”

As stated by Dr. Peter Mansfield, a physician from the UK and advisory board member of the recent government review of fluoridation (McDonagh et al 2000):

“No physician in his right senses would prescribe for a person he has never met, whose medical history he does not know, a substance which is intended to create bodily change, with the advice: ‘Take as much as you like, but you will take it for the rest of your life because some children suffer from tooth decay. ‘ It is a preposterous notion.”

Fluoridation is UNNECESSARY because:

1) Children can have perfectly good teeth without being exposed to fluoride.
2) The promoters (CDC, 1999, 2001) admit that the benefits are topical not systemic, so fluoridated toothpaste, which is universally available, is a more rational approach to delivering fluoride to the target organ (teeth) while minimizing exposure to the rest of the body.
3) The vast majority of western Europe has rejected water fluoridation, but has been equally successful as the US, if not more so, in tackling tooth decay.
4) If fluoride was necessary for strong teeth one would expect to find it in breast milk, but the level there is 0.01 ppm , which is 100 times LESS than in fluoridated tap water (IOM, 1997).
5) Children in non-fluoridated communities are already getting the so-called “optimal” doses from other sources (Heller et al, 1997). In fact, many are already being over-exposed to fluoride.

Fluoridation is INEFFECTIVE because:

1) Major dental researchers concede that fluoride’s benefits are topical not systemic (Fejerskov 1981; Carlos 1983; CDC 1999, 2001; Limeback 1999; Locker 1999; Featherstone 2000).
2) Major dental researchers also concede that fluoride is ineffective at preventing pit and fissure tooth decay, which is 85% of the tooth decay experienced by children (JADA 1984; Gray 1987; White 1993; Pinkham 1999).
3) Several studies indicate that dental decay is coming down just as fast, if not faster, in non-fluoridated industrialized countries as fluoridated ones (Diesendorf, 1986; Colquhoun, 1994; World Health Organization, Online).
4) The largest survey conducted in the US showed only a minute difference in tooth decay between children who had lived all their lives in fluoridated compared to non-fluoridated communities. The difference was not clinically significant nor shown to be statistically significant (Brunelle & Carlos, 1990).
5) The worst tooth decay in the United States occurs in the poor neighborhoods of our largest cities, the vast majority of which have been fluoridated for decades.
6) When fluoridation has been halted in communities in Finland, former East Germany, Cuba and Canada, tooth decay did not go up but continued to go down (Maupome et al, 2001; Kunzel and Fischer, 1997, 2000; Kunzel et al, 2000 and Seppa et al, 2000).

Fluoridation is UNSAFE because:

1) It accumulates in our bones and makes them more brittle and prone to fracture. The weight of evidence from animal studies, clinical studies and epidemiological studies on this is overwhelming. Lifetime exposure to fluoride will contribute to higher rates of hip fracture in the elderly.
2) It accumulates in our pineal gland, possibly lowering the production of melatonin a very important regulatory hormone (Luke, 1997, 2001).
3) It damages the enamel (dental fluorosis) of a high percentage of children. Between 30 and 50% of children have dental fluorosis on at least two teeth in optimally fluoridated communities (Heller et al, 1997 and McDonagh et al, 2000).
4) There are serious, but yet unproven, concerns about a connection between fluoridation and osteosarcoma in young men (Cohn, 1992), as well as fluoridation and the current epidemics of both arthritis and hypothyroidism.
5) In animal studies fluoride at 1 ppm in drinking water increases the uptake of aluminum into the brain (Varner et al, 1998).
6) Counties with 3 ppm or more of fluoride in their water have lower fertility rates (Freni, 1994).
7) In human studies the fluoridating agents most commonly used in the US not only increase the uptake of lead into children’s blood (Masters and Coplan, 1999, 2000) but are also associated with an increase in violent behavior.
8) The margin of safety between the so-called therapeutic benefit of reducing dental decay and many of these end points is either nonexistent or precariously low.

Fluoridation is INEQUITABLE, because:

1) It will go to all households, and the poor cannot afford to avoid it, if they want to, because they will not be able to purchase bottled water or expensive removal equipment.
2) The poor are more likely to suffer poor nutrition which is known to make children more vulnerable to fluoride’s toxic effects (Massler & Schour 1952; Marier & Rose 1977; ATSDR 1993; Teotia et al, 1998).
3) Very rarely, if ever, do governments offer to pay the costs of those who are unfortunate enough to get dental fluorosis severe enough to require expensive treatment.

Fluoridation is INEFFICIENT and NOT COST-EFFECTIVE because:

1) Only a small fraction of the water fluoridated actually reaches the target. Most of it ends up being used to wash the dishes, to flush the toilet or to water our lawns and gardens.
2) It would be totally cost-prohibitive to use pharmaceutical grade sodium fluoride (the substance which has been tested) as a fluoridating agent for the public water supply. Water fluoridation is artificially cheap because, unknown to most people, the fluoridating agent is an unpurified hazardous waste product from the phosphate fertilizer industry.
3) If it was deemed appropriate to swallow fluoride (even though its major benefits are topical not systemic) a safer and more cost-effective approach would be to provide fluoridated bottle water in supermarkets free of charge. This approach would allow both the quality and the dose to be controlled. Moreover, it would not force it on people who don’t want it.

Fluoridation is UNSCIENTIFICALLY PROMOTED. For example:

1) In 1950, the US Public Health Service enthusiastically endorsed fluoridation before one single trial had been completed.
2) Even though we are getting many more sources of fluoride today than we were in 1945, the so called “optimal concentration” of 1 ppm has remained unchanged.
3) The US Public health Service has never felt obliged to monitor the fluoride levels in our bones even though they have known for years that 50% of the fluoride we swallow each day accumulates there.
4) Officials that promote fluoridation never check to see what the levels of dental fluorosis are in the communities before they fluoridate, even though they know that this level indicates whether children are being overdosed or not.
5) No US agency has yet to respond to Luke’s finding that fluoride accumulates in the human pineal gland, even though her finding was published in 1994 (abstract), 1997 (Ph. D. thesis), 1998 (paper presented at conference of the International Society for Fluoride Research), and 2001 (published in Caries Research).
6) The CDC’s 1999, 2001 reports advocating fluoridation were both six years out of date in the research they cited on health concerns.

Fluoridation is UNDEFENDABLE IN OPEN PUBLIC DEBATE.

The proponents of water fluoridation refuse to defend this practice in open debate because they know that they would lose that debate. A vast majority of the health officials around the US and in other countries who promote water fluoridation do so based upon someone else’s advice and not based upon a first hand familiarity with the scientific literature. This second hand information produces second rate confidence when they are challenged to defend their position. Their position has more to do with faith than it does with reason.

Those who pull the strings of these public health ‘puppets’, do know the issues, and are cynically playing for time and hoping that they can continue to fool people with the recitation of a long list of “authorities” which support fluoridation instead of engaging the key issues. As Brian Martin made clear in his book Scientific Knowledge in Controversy: The Social Dynamics of the Fluoridation Debate (1991), the promotion of fluoridation is based upon the exercise of political power not on rational analysis. The question to answer, therefore, is: “Why is the US Public Health Service choosing to exercise its power in this way?”

Motivations – especially those which have operated over several generations of decision makers – are always difficult to ascertain. However, whether intended or not, fluoridation has served to distract us from several key issues. It has distracted us from:

a) The failure of one of the richest countries in the world to provide decent dental care for poor people.
b) The failure of 80% of American dentists to treat children on Medicaid.
c) The failure of the public health community to fight the huge over consumption of sugary foods by our nation’s children, even to the point of turning a blind eye to the wholesale introduction of soft drink machines into our schools. Their attitude seems to be if fluoride can stop dental decay why bother controlling sugar intake.
d) The failure to adequately address the health and ecological effects of fluoride pollution from large industry. Despite the damage which fluoride pollution has caused, and is still causing, few environmentalists have ever conceived of fluoride as a ‘pollutant.’
e) The failure of the US EPA to develop a Maximum Contaminant Level (MCL) for fluoride in water which can be scientifically defended.
f) The fact that more and more organofluorine compounds are being introduced into commerce in the form of plastics, pharmaceuticals and pesticides. Despite the fact that some of these compounds pose just as much a threat to our health and environment as their chlorinated and brominated counterparts (i.e. they are highly persistent and fat soluble and many accumulate in the food chains and our body fat), those organizations and agencies which have acted to limit the wide-scale dissemination of these other halogenated products, seem to have a blind spot for the dangers posed by organofluorine compounds.

So while fluoridation is neither effective nor safe, it continues to provide a convenient cover for many of the interests which stand to profit from the public being misinformed about fluoride.

Unfortunately, because government officials have put so much of their credibility on the line defending fluoridation, it will be very difficult for them to speak honestly and openly about the issue. As with the case of mercury amalgams, it is difficult for institutions such as the American Dental Association to concede health risks because of the liabilities waiting in the wings if they were to do so.

However, difficult as it may be, it is nonetheless essential – in order to protect millions of people from unnecessary harm – that the US Government begin to move away from its anachronistic, and increasingly absurd, status quo on this issue. There are precedents. They were able to do this with hormone replacement therapy.

But getting any honest action out of the US Government on this is going to be difficult. Effecting change is like driving a nail through wood – science can sharpen the nail but we need the weight of public opinion to drive it home. Thus, it is going to require a sustained effort to educate the American people and then recruiting their help to put sustained pressure on our political representatives. At the very least we need a moratorium on fluoridation (which simply means turning off the tap for a few months) until there has been a full Congressional hearing on the key issues with testimony offered by scientists on both sides. With the issue of education we are in better shape than ever before. Most of the key studies are available on the internet and there are videotaped interviews with many of the scientists and protagonists whose work has been so important to a modern re-evaluation of this issue.

With this new information, more and more communities are rejecting new fluoridation proposals at the local level. On the national level, there have been some hopeful developments as well, such as the EPA Headquarters Union coming out against fluoridation and the Sierra Club seeking to have the issue re-examined. However, there is still a huge need for other national groups to get involved in order to make this the national issue it desperately needs to be.

I hope that if there are RFW readers who disagree with me on this, they will rebut these arguments. If they can’t than I hope they will get off the fence and help end one of the silliest policies ever inflicted on the citizens of the US. It is time to end this folly of water fluoridation without further delay. It is not going to be easy. Fluoridation represents a very powerful “belief system” backed up by special interests and by entrenched governmental power and influence.

Paul Connett. All references cited can be found at http://www.slweb.org/bibliography.html

All references cited can be found at http://www.slweb.org/bibliography.html

2010-03-15 16:44:47